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Supporting Culture of Inquiry

Evidence-Based Practice Center and Fellowship

The Stanford Center for Implementation and Evaluation of Nursing Care Evidence (S.C.I.E.N.C.E.) resides within the Professional Practice and Clinical Improvement Department, providing support for the implementation of evidence-based practices, including:

  • Consultation

  • Education and Training

  • Tools and Resources


  • Ensure excellence in nursing practice

  • Create structures and processes that encourage critical inquiry.

  • Support staff in evaluating practice, identifying gaps, and implementing the best available evidence.


A structured program to support nurses wanting to transform clinical practice.


  • Paid time to complete an EBP implementation project.

  • 32 hours of didactic content

  • Monthly skill-building sessions.

  • One-on-one coaching by an EBP expert

  • Project presentation opportunity

SCIENCE Fellowship Projects - Cohort 1

Utilizing Orthostatic Vital Signs to Reduce Falls in BMT Patients​

​Lydia Sulaiman Kelly, BSN, RN, BMTCN​

Clinical Nurse II


Maintenance flushing of Small Bore Feeding Tubes​

Megan Morey, BS, RN, BSN, CCRN​

Clinical Nurse IV​

Specialty Procedure Team​

Stanford Health Care SCIENCE Fellowship cohort 1

Submitted by:  Mary E. Lough PhD, RN, CCNS, FCCM, FAHA, FCNS, FAAN
Implementation Scientist

The Impact of Preemptive Plerixafor on Hematopoietic Stem Cell Collections Required for Autologous Transplant: A Single Center Experience

In May 2022, Victoria Osgood BSN, RN, CCRN, CNN attended the American Society for Apheresis (AFSA) in Philadelphia, PA to present her evidence-based practice research, a monumental moment of her nursing career. Victoria has been an AFSA member for as long as she has worked as an apheresis nurse, 19 years. The science in apheresis medicine incorporates other disciplines and is vey specialized, which makes it a unique field to work in.

Victoria’s research challenged an existing Bone Marrow Transplant (BMT) protocol and examined if early intervention with Plerixafor, a bone marrow stimulant medication. The goal of any apheresis protocol is to minimize collection days and maximize Hematopoietic Stem Cell collection efficiency. Victoria reviewed the data prior to and after the revised protocol in patients undergoing stem cell transplantation for Multiple Myeloma (MM).

Success Outcomes:

  • Patients that received plerixafor for low blood cell count numbers had a mean of 2 collections days, which was comparable to patients who had higher cell counts and may suggested that some patients benefitted from this intervention.

  • Peripheral blood CD34+ counts were not a consistent predictor of collection outcomes. 

Victoria’s takeaway:

“I learned a lot from working on this research project and feel very fortunate for the great advisors who guided me through the uncharted experience of writing a research paper and for the opportunity Stanford gave me.”

Submitted by:  Victoria Osgood RN, CCRN, CNN, Apheresis Clinical Nurse IV

CELT & RITE Programs
Improvement Training 

Clinical Effectiveness Leadership Training (CELT)

The CELT program was developed to provide healthcare professionals, including physicians, nurses, and administrative professionals, with the skills, tools, and information needed to become leaders of healthcare improvements. With CELT, there is a significant time commitment of 10 sessions, including a cohort graduation.  The sessions incorporate lecture-style learning and workshops.


During the classes, topics include: 

Throughout the program, each team completes a process improvement project and participants are empowered to become visionary change agents.

Learn more about SHC's CELT program here.

Leadership Development

Common improvement methods and their deployment

Analyzing data and evidence appropriately to drive improvement. 

Becoming an effective clinical leader

How to utilize quality improvement methods and tools

Managing group dynamics and interpersonal relationships

Realizing Improvement through Team Empowerment (RITE)

The RITE program consists of 10 educational sessions and a cohort graduation. This program is designed for all healthcare staff who have a meaningful improvement project that they would like to work on while learning about quality improvement and project management. In addition to structured sessions, each team watches prepared video tutorials and meets outside the classroom in order to discuss and apply their learned knowledge to their chosen improvement project. The classroom educational topics include:

  • Project and team management

  • Developing a culture of improvement 

  • Improvement concepts 

  • Intervention testing and change management 

Click here to view the past cohorts and learn more about these great SHC resources.


Improving the Appropriate Use of Central Lines in the Cardiovascular Intensive Care Unit 
Using a Central Line De-escalation Algorithm to Reduce CLABSI

SHC Clabsi CELT Team
The goal was not about avoidance or blind removal, but an “authentic” assessment of central line necessity based on clinical need.

 A nurse led interprofessional group was united through the Clinical Effectiveness Leadership Training (CELT) program with the goal of improving patient safety and quality of care and reducing Central Line Blood Stream Infection (CLABSI) cases on cardiovascular ICU (CVICU) units. 

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